Tag: innovation

US COVID-19 failures

The failures are fractal, hence I’ll collect different takes from different perspectives.

The United States, long accustomed to thinking of itself as the best, most efficient, and most technologically advanced society in the world, is about to be proved an unclothed emperor.

the pandemic outed 100Ms as dumb fucks, not really news, but still depressing.

the United States underperformed across the board, and its errors compounded. The dearth of tests allowed unconfirmed cases to create still more cases, which flooded the hospitals, which ran out of masks, which are necessary to limit the virus’s spread. Twitter amplified Trump’s misleading messages, which raised fear and anxiety among people, which led them to spend more time scouring for information on Twitter. Even seasoned health experts underestimated these compounded risks.

Also, this analysis is far too kind on the establishment: so many institutional failures and inertia at the CDC and FDA that have nothing to do with this narrative.
The following piece argued that all the pandemic planning was a waste of time.

The failure of the United States government to respond to the coronavirus was not a failure of foresight. It was a failure to create a coherent strategy and to provide clear lines of authority to implement it. To prepare for the next pandemic, we need to end our current proliferation of planning mandates and overlapping agency authorities (such as that of the Assistant Secretary for Response and Preparedness), strengthen the pandemic response ability of one agency (preferably the Centers for Disease Control and Prevention), and reform our current National Emergency Act to allow clear delegation of emergency power. Only by examining our current failures and rectifying them, most importantly, by combining authority, responsibility, and accountability in the right hands, can we make sure that our next Pandemic Preparedness Act is not an embarrassment to its name.

We also lost a lot of process knowledge to be able to pivot quickly:

US factories are as productive as ever but they’ve lost the process knowledge needed to retool quickly in a crisis.

COVID-19 crisis reveals paralytic nature of America’s regulatory order:

We need an immediate intervention to break America free from its bureaucratic addiction.

States can’t even redirect 0.3% of their budget:

States and local public health officials have warned for months that they would need more than $8B in additional funding to stand up the infrastructure needed to administer vaccines. Total state and local spending is about $3.7 trillion, $2.3 trillion from the states alone. $8B is how much of that? Our states cannot come up with 0.3% of their budgets to meet the greatest emergency in our lifetimes?

Meanwhile, alcohol producer can’t make sanitizer:

Worse yet, the FDA reversed course, announcing additional restrictions that effectively prevent any sales, even though ethanol companies had already produced and shipped millions of liters of high-grade alcohol for hand sanitizer.

here’s how things went with contact tracing:

But the effort was frustrated as the CDC’s decades-old notification system delivered information collected at the airports that was riddled with duplicative records, bad phone numbers and incomplete addresses. For weeks, officials tried to track passengers using lists sent by the CDC, scouring information about each flight in separate spreadsheets. “It was insane”

50% crazy

When I invest in biotech, I have a sort of a model for the type of person I’m looking to invest in. There’s sort of a bimodal distribution of scientists. You basically have people who are extremely conventional and will do experiments that will succeed but will not mean anything. These will not actually translate into anything significant, and you can tell that it is just a very incremental experiment. Then you have your various people who are crazy and want to do things that are going to make a very big difference. They’re, generally speaking, too crazy for anything to ever work. You want to find the people who are roughly halfway in between. There are fewer of those people because of these institutional structures and whatnot, but I don’t think they’re nonexistent. My challenge to biotech venture capitalists is to find some of those people who are crazy enough to try something bold, but not so crazy that it’s going to be this mutation where they do 100 things differently.

Physics & Biology

13 tips for engaging with physicists, as told by a biologist this is a great, and unfortunately rare, example of interdisciplinary work:

Understand what ‘I do not understand’ means When physicists do not understand something that you have said about biology, it’s possible that you do not understand that topic either. 2. Seek common ground When a physicist does not understand an aspect of biology, they are not requesting a ‘biology 101’ explanation. In my experience, when physicists ask a biology question, they want to apply the thinking of physics to biology; specifically, they are searching for universal, mathematical explanations. 4. Keep in mind the maths shortfall in biology For most biological phenomena, we don’t have precise equations — unlike in physics. This is not to say that we don’t have maths, but our field needs a lot more detailed quantification. This lack is the Achilles heel of biology, and affects even the concepts we use every day.

there’s also a view from the other side: 12 tips for engaging with biologists, as told by a physicist

Get comfortable being uncomfortable I went from being one of the most knowledgeable people in my research field at the end of my PhD to knowing less than most of the first-year PhD students in my new lab. For me, that meant I was doing something right, but you do have to be OK with taking that hit and spending time building a new skill set Do not blindly accept dogma Challenging prevailing ideas in biology using your perspective can bring about revolutions. I greatly admire colleagues who have upturned decades of accepted dogma using quantitative methods that were not even considered by the biological community.

The US is behind on 5G

No American company makes the devices that transmit high-speed wireless signals. Huawei is the clear leader in the field; the Swedish company Ericsson is a distant second; and the Finnish company Nokia is third. It is almost surprising that the Defense Department allowed the report to be published at all, given the board’s remarkably blunt assessment of the nation’s lack of innovation and one of the biggest impediments to rolling out 5G in the United States: the Pentagon itself. The broadband spectrum needed to create a successful network was reserved not for commercial purposes but for the military.