Tag: collaborative

23AndMe

My SNP for $1000, my 2008 resolution:

groups of customers coming together around shared genotypes and SNPs, comparing notes about their conditions or backgrounds and identifying areas for further scientific research on their own.

2008-05-28: fill out surveys to strengthen the links between your genetic makeup and open research questions. Sounds a lot more fun than “walking for the cure”.
2015-03-15: 23andme enters drugs. This should be very interesting. To date, they have SNPs from 800k people, and that could grow rapidly. I’d expect them to release new higher resolution kits and make them available at cost to their customers.

23andMe, the Google -backed personal genetics startup, will no longer just sell tests to consumers, or genetic data to pharmaceutical companies. This morning, it announced that it plans to start inventing medicines itself.

2015-06-18: 23andme has 1M customers now. I’m pleased to be among the first 0.2% 🙂
2019-07-16: 23andMe Chip Updates

100s of 23andMe customers tested on those earlier chips have pleaded with the company for some way to get access to its latest features, like the health reports and improved ancestry estimates. Many worried about whether their old data was accurate.

2023-06-01: Now they’re doing cancer drugs, but it’s not obvious why their SNPs matter all that much? It feels they need to rebase their approach on much more powerful technology like full genome sequencing. That said, I’ve yet to receive a benefit from my Nebula 30x DNA sequencing.

23ME’610 is designed to do something similar, by binding to a receptor called CD200R1, which was identified as a promising anti-cancer target by 23andMe scientists studying the 23andMe database. CD200R1 is a cell surface receptor protein that is mostly expressed on human immune cells, specifically cancer-fighting T cells and myeloid cells. Tumor cells can express CD200, the only known binding partner for CD200R1, and use this regulatory protein to turn off the activity of T cells. A drug that blocks the ability of CD200 to bind to CD200R1 may activate T cells and enhance their ability to kill cancer cells.

Blogs Meet Forums 2.0

MTCS is about rescuing the huge parts of the web that are still suffering under circa-1997 technologies. I call it the “Dark Web” — all these conversations that are taking place on bulletin boards, forums, and message boards, but they don’t have any of the usability or identity benefits of modern web technologies. And that’s leaving aside niceties like good URLs (for Google indexing) and tagging and rich media support. I mean, you just don’t see a forum where you can easily upload video or audio assets, for example.

i attempted once to wean people off their 1997 era forums. what a wasteland. still, remarkably resilient, just like hotmail.com

Better Debates

Questions would be posed by candidates to each other, as well as by journalists and the public. But an answer would not be the end of that round; in fact, it would only be the beginning. Rebuttals and further rejoinders would be the meat of these conversations. They would not be done on the fly, but would come after the candidates and their staffs had some time to consider their responses. They’d point out flaws and inaccuracies in their opponents’ statements, drilling down into details where warranted. Wherever possible, people would use the Internet’s elemental unit — the hyperlink — to point to source material or other supporting information.

structured debates, fallacy detection.. where is ed?

Confabb

Confabb combines an aggregate database of major conferences, conventions, and trade shows sorted by industry with social networking tools designed to empower conference attendees to improve their overall experience.

Built into the site is a reputation management system to be used by conference attendees, speakers, organizers and administrators allowing people to plan for and attend conferences, and critique and review those they have attended and want to share with colleagues. No other resource contains such a comprehensive listing of events or as robust a tool set for maximizing the conference experience via the live Web.

making conferences relevant again?

Collaborative Mapping business models

Let’s start by fast forwarding to a future where we have economically successful collaborative maps. Then from there we can look back and see how we might get there, what tipping points would be involved. it is possible to decouple the function of ‘ownership’ of a set of geospatial data from the functions that are needed for its upkeep. Indeed such a decoupling could easily lead to a more efficient market around the upkeep of the data. One thing we neglected to mention as well is that a collaborative map opens up the potential for non ‘expert’ contributors to do valuable work, as long as the structure is set up to minimize vandalism and the like.

OSM Army

I’m not convinced that the state of the art in GIS databases has appropriate answers. The OSM community, as ever, creates new cart-tracks across well-paved spaces. The debate is too heated for any but the really committed to follow, the tracks become effaced in debate, but perhaps they’re leading somewhere new. Or as the New Data Model paper puts it, Complexity does not mean that it has to be more complicated.

jo thinks the new OSM data model is more RDF-like, which of course she approves of