Month: December 2020

Custom PCB

A fun look at what custom fabrication can do.

Of course, there’s a lot of email back-and-forth with the PCB shop to clarify things, and it takes an extra week to process the boards, But, it’s very important not to rush the shop when specifying highly bespoke designs because you want the best machine operators to run your boards, not just the ones who happen to be available that day. When things get really challenging, I know that King Credie’s CEO will personally go on the line to supervise production, but this is only possible because I let them prioritize correct results over fast turn delivery – he’s a busy guy, but it’s well worth the wait to get his personal assistance. He’s an engineer at heart and he knows the company’s capabilities like the back of his hand. And finally, it helps if I make it clear to the shop that for risky production runs like this, I will pay 100% of the quoted price, even if the scrap rate is high and they can only do a partial delivery. I’ve rarely been in a situation where the shop has had to adjust delivery quantities because of yield issues. I was lucky in that the bezel process worked on the first try (subsequent iterations were around refining the antenna shape and cosmetic details), but I’ve definitely had challenging PCBs where I’ve had to pay for 2 or 3 goes at process development before I had a process that worked right and yielded well.

Generic Solutions

Fighting a disease through targeting its pathophysiologies is, in a sense, an attempt to outflank it rather than attack it head-on. Instead of looking for the magic bullet that will kill the virus, or the tumor, it’s about making the body an unfriendly place for the disease to be in.

The main advantage to this approach is that there already exists a formidable arsenal to assist in this fight: 9500 drugs approved worldwide.

“We believe that in the bank of drugs we have now, the 9500 drugs there are in the world, we have the answers for virtually all diseases. Around 500 of them are still patented. So there’s opportunity to work through the other 9000 off-patent drugs — the generic drugs — and look at the impact that 1 can have for $1 a day.”
Cureosity is a repository of manually curated knowledge about novel treatments for serious, chronic, and intractable diseases.