Chimeric Immunity

Dr Sachs and Dr Cosimi tricked the body by transplanting a part of the donor’s bone marrow along with the organ. Since the cells of the immune system are derived from stem cells in the bone marrow, these patients go on to develop what is known as chimeric immunity, which blends elements from the immune systems of both the donor and the recipient.

Transplanting immune-system stem cells along with kidneys stops rejection, enables xenotransplantation.

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