Few people have thought as long and as hard about the origin of life and the emergence of complexity in a biosphere as Stuart Kauffman. Medical doctor, geneticist, professor of biochemistry and biophysics, MacArthur Fellow, and member of the faculty of the Santa Fe Institute for a decade, he has sought to discover the principles which might underlie a “general biology”—the laws which would govern any biosphere, whether terrestrial, extraterrestrial, or simulated within a computer, regardless of its physical substrate. an overview of the principles he suspects, but cannot prove, may underlie all forms of life, and beyond that systems in general which are far from equilibrium such as a modern technological economy and the universe itself.